Phase 3 Stroke Trial, Recruiting NCT06715449 Sponsor: University of East Anglia Condition: Stroke
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Phase 3 Stroke Trial, Recruiting

NCT06715449
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older
  • You have had a stroke or mini-stroke (a brief stroke-like episode) where the cause was not clearly identified, confirmed by brain scans (CT or MRI)
  • Scans of the blood vessels in your neck and brain showed no significant blockages or build-up of fatty deposits
  • No known heart-related cause of the stroke was found (such as an irregular heartbeat, blood clots in the heart, certain heart valve problems, or a weakly pumping heart)
  • No other specific cause of the stroke was identified (such as a blood-clotting disorder, inflamed blood vessels, a torn blood vessel, or drug use)
  • You have already been referred to have a small heart monitor device implanted under the skin to check for irregular heart rhythms
  • You are able to read and sign a consent form agreeing to take part

Who may not be able to join:

  • You have already been diagnosed with atrial fibrillation or atrial flutter (specific types of irregular heartbeat)
  • A heart-related cause of your stroke has since been identified
  • You already take SGLT2 inhibitor medication (a type of tablet) for heart failure or diabetes (Type 1 or Type 2)
  • You have a history of, or risk factors for, a dangerous condition called diabetic ketoacidosis, including very restricted eating or a history of alcohol misuse
  • You have had an allergic reaction to empagliflozin (the study medication) or any of its ingredients
  • You already have another implanted heart device, such as a pacemaker or defibrillator, that would make the implanted heart monitor unnecessary
  • You have a condition such as dementia that could affect the results of the study or make it difficult to participate
  • You do not wish to take part in the trial

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 01603592534

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
University of East Anglia
Registry
ClinicalTrials.gov
Start date
22 November 2024
Est. completion
1 July 2026

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Change in left atrial reservoir strain

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov