Phase 2 Lymphoma Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults aged 18 or older, of any gender
• People who have been diagnosed (confirmed by tissue testing) with a relapsed or returning form of a slow-growing T-cell or NK-cell lymphoma, where at least one previous treatment has not worked or was not tolerated, or where no standard effective treatment is currently available
• People whose condition meets the specific treatment criteria set by the trial site
• People who are reasonably active and able to care for themselves, based on a standard health performance scale (scores 0–2, meaning fully active to capable of self-care but unable to do physical work)
• People whose liver, kidney, and heart are functioning adequately, based on blood test results and heart measurements within specific ranges (confirm with trial site for exact values)
• People with an expected survival of at least 3 months
• People who agree to use effective contraception during the trial and for 6 months after the last dose of the study drug (applies to both male and female participants who are capable of having children)
• People who have completed any previous cancer treatments (including radiotherapy, chemotherapy, hormone therapy, surgery, or targeted therapy) at least 4 weeks before joining the trial
• People who have not taken part in another clinical trial within the past month
• People who are willing to give written informed consent to participate

Who may not be able to join:

• People who have previously taken any JAK inhibitor medications
• People who have difficulty swallowing, poor nutrient absorption, or ongoing gut or digestive conditions that could affect how the study drug is absorbed
• People who currently have an active infection (such as pneumonia) caused by a virus, bacteria, or fungus that requires treatment
• People with active hepatitis B or C infections, based on specific blood marker results (confirm with trial site for exact definitions)
• People with a history of immune system deficiency, including those who are HIV-positive, have other inherited or acquired immune conditions, have had an organ transplant, or have had a donor bone marrow or stem cell transplant
• People who have had their own stem cells transplanted back into them within the 90 days before starting the trial
• People with serious or uncontrolled heart or cardiovascular conditions
• People with other serious health conditions that the trial doctor believes could put them at risk or interfere with completing the trial, such as uncontrolled high blood pressure, diabetes, or thyroid problems
• People who are pregnant or breastfeeding, or who test positive for pregnancy at the start of the trial
• People who have been diagnosed with or treated for another type of cancer within the past 5 years
• People who, in the trial doctor's judgement, are not suitable for any other reason

Important: Always verify eligibility with the trial site directly before applying.