Motor Neurone Disease Trial, Recruiting (NCT06735014)

Motor Neurone Disease Trial, Recruiting NCT06735014 Sponsor: University of Minnesota Condition: Motor Neurone Disease

Printed from Voxsanity (voxsanity.com.au) — NCT06735014 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Motor Neurone Disease

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial (for people with ALS):

Your symptoms started less than 36 months (3 years) ago
You have been diagnosed with ALS confirmed by one of two standard sets of medical guidelines (El Escorial or Awaji-Shima criteria) — your doctor can confirm which applies to you
A breathing test taken within the last 90 days showed your lungs are working at 60% or more of the expected level for someone your age and size
You are able to make your own decision about joining the trial and sign a consent form
You are able to read and speak English
You have no health reasons that would make having an MRI scan unsafe for you

Who may not be able to join:

People who have any condition that makes having an MRI scan unsafe (such as certain metal implants — confirm with trial site)
People who are unable to follow instructions during the study
People whose neurological (brain and nervous system) examination at the start of the study shows significant unexpected problems unrelated to their condition (this criterion appears to apply mainly to healthy comparison participants — confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 26 July 2026

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Pramod Pisharady, PhD, University of Minnesota

Phone: 612-624-4911

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT06735014

Sponsor: University of Minnesota

Phase: Not Applicable

Status: Recruiting

Condition: Motor Neurone Disease

Trial contact: 612-624-4911

More information: https://clinicaltrials.gov/study/NCT06735014

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial (for people with ALS):

Your symptoms started less than 36 months (3 years) ago
You have been diagnosed with ALS confirmed by one of two standard sets of medical guidelines (El Escorial or Awaji-Shima criteria) — your doctor can confirm which applies to you
A breathing test taken within the last 90 days showed your lungs are working at 60% or more of the expected level for someone your age and size
You are able to make your own decision about joining the trial and sign a consent form
You are able to read and speak English
You have no health reasons that would make having an MRI scan unsafe for you

Who may not be able to join:

People who have any condition that makes having an MRI scan unsafe (such as certain metal implants — confirm with trial site)
People who are unable to follow instructions during the study
People whose neurological (brain and nervous system) examination at the start of the study shows significant unexpected problems unrelated to their condition (this criterion appears to apply mainly to healthy comparison participants — confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 26 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Not Applicable

Sponsor

University of Minnesota

Registry

ClinicalTrials.gov

Start date

15 September 2024

Est. completion

31 August 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Fiber Density; Fiber Cross-Section; Orientation Dispersion; Intracellular Volume Fraction; Free Water; Cortical Thickness; Spinal Cord Cross-Sectional Area; Spinal Cord Corticospinal Tract (CST) Fractional Anisotropy (FA)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov