Schizophrenia Trial, Recruiting NCT06745479 Sponsor: Rutgers, The State University of New Jersey Condition: Schizophrenia
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Schizophrenia Trial, Recruiting

NCT06745479
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 18 and 50 years old
  • You are able to understand and agree to take part in the study on your own
  • You can communicate fluently in English
  • You are willing and able to follow the study's requirements, including signing a consent form and completing study tasks
  • You have the thinking ability to understand the tasks involved, with an estimated IQ above 70
  • (If you have schizophrenia) You have been diagnosed with schizophrenia or schizoaffective disorder as your main condition
  • (If you do not have schizophrenia) You may be selected to participate as a comparison participant, matched to someone in the schizophrenia group based on age, sex, race/ethnicity, and education level

Who may not be able to join:

  • You appear to be or have disclosed being under the influence of alcohol or drugs at the time of the study
  • You currently use substances such as cocaine or heroin (other than nicotine, alcohol, or cannabis) on a regular basis
  • You have a long history of serious problems with substance use (other than nicotine or tobacco)
  • You have a significant physical health condition or a neurological condition, such as Parkinson's disease or a history of strokes
  • You have a history of traumatic brain injury or a head injury that caused a prolonged loss of consciousness or lasting effects on your thinking or behaviour
  • You have had electroconvulsive therapy (ECT) within one month of joining the study
  • You have a history of seizures or epilepsy
  • You have a psychiatric or medical condition that is currently untreated or not well managed
  • You have an intellectual disability
  • You have any condition or implant that makes it unsafe for you to have an MRI scan (confirm with trial site)
  • (If you do not have schizophrenia) You have a history of significant problems with substance use, other than nicotine, alcohol, or mild-to-moderate cannabis use
  • (If you do not have schizophrenia) You have been diagnosed with, or have a close family member diagnosed with, a significant psychiatric condition such as bipolar disorder, a psychotic disorder, or a Cluster A personality disorder (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: David Zald, PhD, Rutgers University

Phone: 732-235-6438

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Rutgers, The State University of New Jersey
Registry
ClinicalTrials.gov
Start date
7 January 2025
Est. completion
30 April 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Nucleus Accumbens Brain Activation; Gambling Choice Behavior

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov