Phase 3 Stroke Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are showing signs of an acute stroke caused by a blocked blood vessel, where the stroke started within the last 24 hours, or who woke up with stroke symptoms (if the midpoint of their sleep was within the last 24 hours)
- People whose stroke started between 4.5 and 24 hours ago and who meet specific treatment guidelines for clot-dissolving therapy (confirm with trial site)
- People who took a newer type of blood thinner (such as apixaban, rivaroxaban, or dabigatran) between 4 and 48 hours before the stroke started
- People aged 18 or older
- People for whom informed consent has been obtained, as required by local ethics rules
Who may not be able to join:
- People who are planned to have a procedure to physically remove or unblock the clot through a blood vessel
- People whose blood clotting test result (APTT) is above 40 seconds
- People who had significant physical disability before the stroke (a pre-stroke disability score above 2 on a standard scale)
- People who have bleeding inside the skull or brain, including any type of brain or spinal bleed
- People who have a previous history of bleeding inside the brain
- People who experienced a serious head injury or stroke in the last 3 months
- People who have a brain tumour or a very large brain aneurysm
- People who had brain or spinal surgery in the last 3 months
- People who had major surgery in the last 2 weeks
- People who had bleeding in the stomach, bowel, or urinary tract in the last 3 weeks
- People who are currently bleeding internally in an organ
- People who have a tear in the main artery leaving the heart (aortic dissection)
- People who had a needle inserted into an artery in the last week in a location that is difficult to apply pressure to stop bleeding
- People with very high blood pressure (top number 180 mmHg or higher, or bottom number 100 mmHg or higher)
- People with a tendency to bleed, including a low platelet count (below 100 × 10⁹/L) or similar conditions
- People who received a low-molecular-weight heparin blood thinner injection in the last 24 hours
- People taking warfarin (an older blood thinner) with certain blood test results above set limits (INR above 1.7 or PT above 15 seconds)
- People whose blood sugar level is either too low (below 2.8 mmol/L) or too high (above 22.22 mmol/L)
- People whose brain scan shows a large area of stroke damage (covering one-third or more of a major brain region called the middle cerebral artery territory)
- People excluded based on the treating doctor's clinical judgement
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 8613958007213
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Excellent recovery assessed by the ratio of modified Rankin Scale (mRS) score of 0-1 (%) at 90 ± 7 days
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.