Osteoarthritis Trial, Recruiting NCT06781463 Sponsor: University of Chicago Condition: Osteoarthritis
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Osteoarthritis Trial, Recruiting

NCT06781463
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older
  • You have knee pain in one or both knees that has been diagnosed as knee osteoarthritis (if both knees are affected, only the more severely affected knee would be included)
  • Your knee osteoarthritis has been confirmed by a standing X-ray and rated as Grade 1, 2, or 3 on a standard medical scale
  • Your knee pain has lasted more than 6 months and has not improved enough with common pain relief treatments such as anti-inflammatory medications or acetaminophen
  • You are either not a candidate for knee replacement surgery, or you personally prefer to try a less invasive procedure called Genicular Artery Embolization (GAE) instead

Who may not be able to join:

  • You currently have an active cancer diagnosis
  • You have an active infection in the knee being treated
  • You have certain blood clotting test results that fall outside acceptable ranges (confirm with trial site)
  • You have had a steroid injection in the affected knee within the past 3 months
  • You have rheumatoid arthritis or a similar inflammatory joint condition
  • You have had previous surgery on the affected knee, not counting keyhole (arthroscopy) surgery
  • Your knee osteoarthritis is rated as Grade 4 (the most severe level) on the standard medical scale
  • You are pregnant or planning to become pregnant
  • Your kidneys are not functioning well enough, based on a specific kidney function test result (confirm with trial site)
  • You have previously had a severe allergic reaction to the dye used in imaging scans (iodinated contrast)
  • You have moderate to severe pain in other joints in your lower legs or hips
  • Your body weight exceeds 400 lbs, as this may make the imaging procedure unsafe
  • You have significant circulation problems in the leg being treated (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 5 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 773.795.7030

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 October 2023
Est. completion
1 October 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 5 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov