Phase 3 Asthma Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Children aged between 2 and 17 years old (before their 18th birthday).
- Children who have been diagnosed with asthma or an asthma-like condition by a doctor, including an emergency department doctor.
- Children whose asthma is considered moderate to severe after already receiving three rounds of inhaled breathing treatments (salbutamol and ipratropium) in the emergency department, based on a specific symptom score of 5 or higher.
Who may not be able to join:
- Children who have already received intravenous magnesium (a medication given through a drip) within the 24 hours before arriving at the emergency department.
- Children who need immediate breathing support on arrival, such as a special high-flow oxygen mask, a breathing machine, or a breathing tube inserted into the airway. (Note: basic supplemental oxygen on its own does not disqualify a child.)
- Children known to have kidney disease, a long-term lung condition, a neurological condition, a heart condition, or another serious ongoing illness.
- Children with a known allergy or sensitivity to magnesium sulfate.
- Children who have previously taken part in this trial.
- Families where neither English nor French is understood well enough to give informed consent.
- Families without access to a phone or email, or who would be otherwise unavailable for follow-up contact after the visit.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Suzanne Schuh, MD, The Hospital for Sick Children
Phone: 416-813-7654
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Pediatric Respiratory Assessment Measure (PRAM) score: This score ranges from 0-12. A score from 0-3 is mild, 4-7 moderate and 8-12 severe. A low score is a better outcome and a high score is a worse outcome.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.