Alzheimer's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are willing and able to understand and sign a consent form agreeing to take part in the study.
- You are 60 years old or older.
- You have been diagnosed with Alzheimer's disease (possible or probable), or have mild memory and thinking problems (mild cognitive impairment) that have been linked to Alzheimer's through brain scans or fluid tests.
- A doctor has assessed your condition and found it ranges from mild memory/thinking problems to moderate dementia, based on a standard rating scale.
- You are experiencing emotional or mood-related symptoms — such as depression, anxiety, irritability, elevated mood, or low motivation — and these symptoms reach a certain level of severity on a standard questionnaire.
- You have a caregiver who is willing to be present during treatment sessions and complete questionnaires as part of the study.
- You can speak and read in English.
- Your medications have been at a stable dose for at least one month.
- You have access to a reliable broadband internet connection at home.
For the caregiver (if applicable):
- You are an adult who provides unpaid care for the person enrolled in the study.
- You have enough mental capacity to give verbal consent to take part in the caregiver part of the study.
- You are able to read, write, hear, and communicate well enough to answer questions about the participant's health and help during treatment sessions.
Who may not be able to join:
- You have unstable or poorly controlled medical conditions (such as unstable chest pain, uncontrolled diabetes or high blood pressure, or advanced cancer) that a doctor feels would make participation unsafe.
- You have a history of serious psychiatric conditions such as bipolar disorder, schizophrenia, or manic depression.
- You have a history of epilepsy.
- You have any metal objects in your head or skull, or anywhere that could interfere with the brain stimulation used in this study.
- You have had thoughts of suicide with some intention to act on them in the past 3 months, as assessed by a standard scale.
- You are unwilling to have an MRI scan at the start of the study and during an early check-in period, unless you have a confirmed medical reason why MRI is unsafe for you (such as having a pacemaker or other implanted metal).
- You are currently taking part in another clinical trial involving a treatment or therapy.
For the caregiver (if applicable):
- You do not meet all of the caregiver inclusion criteria listed above.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Thiago Macedo e Cordeiro, MD, MSc, The University of Texas Health Science Center at San Antonio
Phone: 210-450-7055
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Neuropsychiatric Inventory Questionnaire (NPI-Q) severity score; Brief Dimensional Apathy Scale (bDAS); Caregiver version of the Irritability Questionnaire (IrQ) How often; Caregiver version of the Irritability Questionnaire (IrQ) How much; Cornell Scale for Depression in Dementia (CSDD); Generalized Anxiety Disorder-7 Scale (GAD-7); Montreal Cognitive Assessment (MoCA)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.