Phase 2 Ovarian Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are 18 years of age or older
• You are able to carry out daily activities with little to no limitation, or with some limitations but still able to care for yourself (your doctor will assess this)
• You are willing and able to give your agreement to participate in the study
• You have been diagnosed with a specific type of ovarian cancer called high-grade serous ovarian carcinoma, confirmed by a tissue sample test
• Your ovarian cancer has continued to grow or came back within 6 months of your last platinum-based chemotherapy treatment (meaning it is resistant or not responding to that treatment)
• You are able to receive standard chemotherapy treatments approved for ovarian cancer
• Your doctors expect you to live for at least 2 months
• Your blood counts are at acceptable levels, meaning your white blood cells, platelets, and hemoglobin (red blood cell measure) meet minimum levels without a recent blood transfusion
• Your liver is working well enough, based on blood test results
• Your kidneys are working well enough, based on blood test results
• Your blood clotting levels are within an acceptable range (unless you are already on blood-thinning medication)
• If you could become pregnant, you must agree to use highly effective birth control during the study and for at least 3 months after your last chemotherapy dose
• If you could become pregnant, you must have a negative pregnancy blood test within 72 hours before starting the study medication
• You have no medical reasons that would prevent you from taking a medication called telmisartan, and you have not taken a type of blood pressure medication called an ACE inhibitor in the 6 weeks before starting telmisartan on this trial
• Your systolic blood pressure (the top number in a blood pressure reading) is at or above 110 mmHg when you join and throughout the study

Who may not be able to join:

• You are unable or unwilling to give your agreement to participate
• You have a significant liver disease that is currently active, such as viral hepatitis, alcohol-related liver disease, or liver scarring (cirrhosis); however, patients with certain managed hepatitis B or C conditions may still be considered (confirm with trial site)
• You are experiencing a severe, dangerous spike in blood pressure (hypertensive urgency or emergency)
• You are currently incarcerated or homeless
• You are pregnant or breastfeeding
• You are under 18 years of age
• You are currently taking a medication called lithium in any form
• You received certain medications called rituximab or amifostine within the last 30 days before starting the study medication
• You have a serious active infection that requires treatment
• You have significant heart or blood vessel problems, such as a heart attack or stroke in the past 6 months, unstable chest pain, certain levels of heart failure, or a serious irregular heartbeat requiring medication
• You have any other condition, treatment, or health issue that, in your doctor's opinion, could interfere with the trial results or would not be in your best interest
• You are currently taking a medication called ramipril
• Your standard chemotherapy treatment includes a medication called bevacizumab
• You are HIV-positive and your HIV viral load is not undetectable by standard testing methods

Important: Always verify eligibility with the trial site directly before applying.