Phase 2 Oesophageal Cancer Trial, Recruiting NCT06819566 Sponsor: Asan Medical Center Condition: Oesophageal Cancer
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Phase 2 Oesophageal Cancer Trial, Recruiting

NCT06819566
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 19 and 79 years old.
  • Your liver function has been rated as "Child-Pugh Class A," meaning your liver is still functioning reasonably well (confirm with trial site).
  • You have been diagnosed with advanced liver cancer (Barcelona Clinic Liver Cancer stage C) and have not yet received any systemic (whole-body) cancer treatment for it.
  • You are generally able to carry out daily activities, with little to no limitation from your illness (ECOG performance score of 0–1; confirm with trial site).
  • Your blood test results meet certain minimum levels, including red blood cells, white blood cells, platelets, and blood clotting ability (confirm specific numbers with trial site).
  • You have had a camera examination of your upper digestive tract (endoscopy) within the past six months before starting treatment.
  • You are not breastfeeding, and if you or your partner could become pregnant, you are using contraception or have no plans for pregnancy.
  • You have been fully informed about the trial and have agreed in writing to take part.

Who may not be able to join:

  • You have already received systemic (whole-body) cancer treatment for advanced liver cancer.
  • More than half of your liver is affected by the tumor.
  • You have a tumor blocking the main blood vessel leading to your liver (main portal vein or both main branches) (confirm with trial site).
  • You have previously had a liver transplant.
  • You currently have another cancer that is not controlled, unless you have been cancer-free from it for more than two years.
  • You have other serious health conditions that are not well controlled and require treatment.
  • You have had bleeding from swollen veins in your food pipe (esophagus) or stomach in the past.
  • You have previously had a procedure to treat swollen veins in your digestive tract, such as certain endoscopic treatments, a liver shunt procedure, or surgery for this purpose (confirm with trial site).
  • You have taken blood-thinning or anti-clotting medications within the week before joining the study.
  • Your baseline endoscopy showed significant swollen veins in your stomach or certain warning signs of bleeding risk (confirm with trial site).
  • You are currently pregnant.
  • You are unable to understand the trial information or sign a consent form.
  • The trial doctor has decided, for any other reason, that the trial is not appropriate for you.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Jihyun An, MD, PhD, Gastroenterology and Hepatology, Hanyang University College of Medicine, Guri, Republic of Korea

Phone: +82-2-3010-3190

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
28 May 2025
Est. completion
31 December 2026

Where this trial is recruiting

🇰🇷 South Korea

Primary endpoints

The incidence of esophageal variceal bleeding at 6 months

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov