Prostate Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 or older who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer)
- People with a general health and activity level rated as fully active or restricted only in physically strenuous activity (ECOG score of 0 or 1)
- People whose PSA (a prostate-related protein measured in the blood) is not currently going down, based on two tests taken at least one week apart in the past two months
- People with a body mass index (BMI) between 20 and 35 kg/m²
- People who have had prior prostate cancer treatment are eligible, as long as the last dose was more than two weeks ago — but prior treatment is not required
- People who have previously taken steroids may be eligible if the last dose was more than two weeks ago and they are able to stop taking them
- People whose liver function blood tests are within an acceptable range (confirm specific values with the trial site)
- People whose kidneys are functioning at an acceptable level, based on a standard kidney function measurement (confirm with trial site)
- People whose blood counts — including white blood cells, platelets, and haemoglobin — are within acceptable ranges (confirm specific values with trial site)
- People whose blood salt and mineral levels (such as sodium, potassium, magnesium, and others) fall within specified normal ranges (confirm specific values with trial site)
- People who are willing and able to sign a written consent form after having the study explained to them
- If soft tissue spread of cancer is present and can be biopsied, people who agree to have that biopsy performed
- If cancer is localised to the prostate, people who agree to a prostate biopsy or surgical removal of the prostate on day 8, 9, or 10 of the trial
Who may not be able to join:
- People with a low general health or activity level (ECOG score of 2 or higher)
- People who have unintentionally lost 5% or more of their body weight in the past three months
- People with diabetes, defined as having an HbA1c blood test result of 6.5% or higher, or who are currently taking any diabetes medications
- People with an active, uncontrolled infection (people with a history of HIV may still be considered eligible if certain specific conditions are met — confirm with trial site; people with a history of hepatitis C may also be considered eligible if they have completed curative treatment and the virus is no longer detectable — confirm with trial site)
- People currently taking immune-suppressing medications, including steroids
- People currently taking water tablets (diuretics) or beta blocker medications (commonly used for heart conditions or blood pressure)
- People with a history of irregular heart rhythm, heart attack, heart valve disease, or high blood pressure in the lungs
- People with an abnormal result on a heart tracing test (ECG/EKG) done at screening
- People who drink alcohol daily
- People whose physical or mental health, in the opinion of the investigating doctor, may affect their ability to safely participate in or comply with the study
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Laura Sena, MD, PhD, SKCCC Johns Hopkins Medical Institution
Phone: 410-502-3825
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Number of adverse events and serious adverse events (SAEs); Number patients who complete 7 days of fasting or the ketogenic very low-calorie diet of ketone supplementation of all enrolled patients.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.