Phase 2 Breast Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are a woman between 18 and 75 years old
• You are generally healthy and able to carry out normal daily activities with little or no limitation (confirm with trial site regarding the specific activity score required)
• Your breast cancer has been confirmed by a biopsy and is at a certain stage — specifically, it has spread to nearby lymph nodes but not to distant parts of the body, or the tumor is a certain size without lymph node involvement (confirm with trial site for exact staging details)
• Your breast cancer has tested strongly positive for a protein called HER2, confirmed by standard laboratory tests
• Your blood test results show that your blood cells (white cells, red cells, and platelets) and your liver and kidney function are all within acceptable ranges, without needing recent blood transfusions or boosting medications
• Your heart is pumping well, with a heart function score above 55% on an ultrasound test
• Your heart's electrical activity (measured by an ECG) is within a normal range
• If you are able to become pregnant, you are willing to use effective contraception during the treatment period and for at least 6 months after your last dose
• You are willing to participate voluntarily, sign a consent form, and attend follow-up appointments

Who may not be able to join:

• Your breast cancer has spread to distant parts of the body (Stage IV)
• You have a type of breast cancer called inflammatory breast cancer
• You have previously received cancer treatment or radiotherapy for any cancer, unless it was a fully cured early-stage cancer such as certain skin cancers or early cervical cancer
• You are currently receiving other cancer treatments as part of another clinical trial
• You had a major operation unrelated to breast cancer within the 4 weeks before starting the study, or you have not fully recovered from such an operation
• You have a serious heart condition, such as heart failure, uncontrolled irregular heartbeat, chest pain requiring medication, significant heart valve disease, evidence of a previous heart attack on an ECG, or poorly controlled high blood pressure
• You have an active uncontrolled infection, a weakened immune system, HIV, another immune deficiency condition, or a history of organ transplant
• You have active hepatitis B or hepatitis C that is not well controlled (confirm with trial site if you have a history of hepatitis B or C, as some cases may still be eligible)
• You have a known allergy to any of the medications used in this trial
• You are pregnant, breastfeeding, have a positive pregnancy test at the start of the trial, or are unwilling to use effective contraception during the trial and for 6 months after the last dose
• You have another serious illness or condition that the trial doctors feel could interfere with your treatment or make participation unsafe

Important: Always verify eligibility with the trial site directly before applying.