Phase 3 Ovarian Cancer Trial, Recruiting NCT06836128 Sponsor: Cairo University Condition: Ovarian Cancer
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Phase 3 Ovarian Cancer Trial, Recruiting

NCT06836128
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Women between 20 and 45 years of age
  • Women who have been diagnosed with Polycystic Ovary Syndrome (PCOS) based on 2023 international guidelines
  • People who are able to give their informed consent to participate

Who may not be able to join:

  • People with a known allergy or sensitivity to either metformin or NAC (N-acetylcysteine)
  • People who have been taking medications that affect blood sugar — such as insulin or sulfonylureas — or hormonal medications within the two months before joining the trial
  • People with high levels of a hormone called prolactin in their blood
  • People who have been diagnosed with diabetes
  • People with a thyroid condition causing abnormal thyroid hormone levels (TSH too high or too low)
  • People with significant kidney problems, where the kidneys are not filtering blood well enough (confirm with trial site)
  • People with serious liver disease, shown by abnormal results across multiple liver function blood tests
  • People who are currently misusing alcohol
  • People who have previously experienced a condition called lactic acidosis while taking metformin
  • People who currently have an active peptic ulcer (a sore in the stomach or digestive tract)
  • People who have a condition called congenital adrenal hyperplasia
  • People who have been diagnosed with Cushing's syndrome
  • People who have a tumour that produces male hormones (androgens)
  • People who have been using spironolactone, other anti-androgen medications, or any hormone therapy for excess hair growth within three months before joining the trial
  • People with severe, unstable heart failure

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Samar F Farid, PhD, Professor and Head of Clinical Pharmacy Department, Faculty of Pharmacy, Cairo University

Phone: +201069342847

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Registry
ClinicalTrials.gov
Start date
1 March 2025
Est. completion
1 February 2026

Where this trial is recruiting

🇪🇬 Egypt

Primary endpoints

Primary outcome will be change in LH/FSH levels.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov