Alzheimer's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
Cognitively normal group:
- People who perform normally on standard memory and thinking tests
- People who have no concerns or complaints about their memory or thinking
Subjective Cognitive Decline (SCD) group:
- People who feel their memory has been persistently getting worse, rather than other areas of thinking
- People who perform normally on standard memory and thinking tests
- People who do not meet the criteria for mild cognitive impairment or dementia
- People who first noticed memory concerns at age 60 or older
- People whose memory concerns started within the last 5 years
- People who are worried about their memory decline
- People who feel their memory is worse compared to others of the same age
Mild Cognitive Impairment (MCI) group:
- People who score in the impaired range on tests in at least one area of thinking (memory, language, or processing speed/planning)
- People who have impaired scores across all three thinking areas (memory, language, and processing speed/planning)
- People who score 9 or higher on a standard questionnaire measuring ability to carry out everyday activities (confirm with trial site)
Alzheimer's dementia group:
- People who meet the medical criteria for dementia and have difficulty with daily activities
- People who have memory problems related to recalling recent events
- People who score 1 or higher on a standard scale used to measure dementia severity (confirm with trial site)
Who may not be able to join:
- People who have had a stroke
- People with major depression or anxiety
- People with other brain or nervous system conditions that affect thinking, such as Parkinson's disease, brain tumours, brain inflammation, or epilepsy
- People whose cognitive difficulties were caused by a head injury
- People with certain whole-body illnesses, such as thyroid problems, syphilis, or HIV
- People with psychosis or a lifelong developmental intellectual disability
- People who have used antibiotics, probiotics, prebiotics, or synbiotics in the past 3 months
- People who are currently using corticosteroids, immune-boosting medications, or immune-suppressing medications
- People who have had major surgery on their digestive tract within the past 5 years
- People with serious gut or digestive conditions — such as irritable bowel syndrome, inflammatory bowel disease, severe gastritis, or other significant digestion or absorption problems — that are known to affect gut bacteria
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Can Sheng, PhD, Affiliated Hospital of Jining Medical University
Phone: 86-18701257298
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
The changes of gut microbiome in the spectrum of AD; The changes of SCFAs in the spectrum of AD; Multi-omics biomarkers associated with conversion to cognitive impairment for SCD subjects
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.