Motor Neurone Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are an adult who has been diagnosed with Motor Neurone Disease (MND) by a specialist neurologist.
- Your breathing tests show that you have too much carbon dioxide building up in your blood during the day, or you have symptoms of breathing difficulties (such as breathlessness when lying flat, waking up at night short of breath, or feeling very drowsy in the mornings), along with confirmed weakness of the main breathing muscle (the diaphragm).
Who may not be able to join:
- You have a cognitive or memory condition that would make it difficult for you to understand the study and give informed consent.
- You have another serious health condition — such as severe heart failure, severe COPD (a chronic lung disease), or very high body weight — that is causing or adding to your breathing problems.
- You need to start breathing support urgently within 24 hours, or you are currently unwell enough to need hospital treatment (for example, IV antibiotics for a lung infection).
- You do not have enough support from family, friends, or care professionals at home to help you use a breathing support machine safely.
- You do not wish to use a breathing support machine at home.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Dariusz Wozniak, Royal Papworth Hospital NHS Foundation Trust
Phone: 01223639619
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Control of respiratory failure defined by daytime partial pressure of carbon dioxide (PaCO2); Patients and carers experiences of starting and managing NIV, and factors that relate to NIV concordance and acceptance.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.