Phase 3 Lymphoma Trial, Recruiting NCT06855810 Sponsor: Institute of Hematology & Blood Diseases Hospital, China Condition: Lymphoma
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Phase 3 Lymphoma Trial, Recruiting

NCT06855810
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Children and young people older than 1 month and younger than 18 years of age
  • People who have been diagnosed with acute lymphoblastic leukemia (a type of blood cancer), confirmed by a bone marrow test
  • People whose leukemia has been identified as the "T-cell" type (called T-ALL) through specialised laboratory testing of the cancer cells

Who may not be able to join:

  • People whose leukemia is the "B-cell" type (B-ALL) rather than T-cell type
  • People diagnosed with a different type of blood cancer called acute myeloid leukemia (AML)
  • People whose leukemia is a mixed or unclear type that cannot be clearly classified, as determined by recognised international medical guidelines
  • People whose leukemia developed from a pre-existing blood condition called chronic myeloid leukemia (CML)
  • People with Down syndrome, or a major inborn or inherited condition that affects how an organ works
  • People whose leukemia developed as a result of a previous cancer treatment (called secondary leukemia)
  • People with a known inherited immune system disorder or an inherited condition affecting the body's metabolism
  • People with a heart defect present from birth that is causing the heart to not pump properly
  • People who have received certain medicines or treatments in the period leading up to the trial — including steroid medicines (glucocorticoids) for 14 days or more, certain targeted medicines called ABL kinase inhibitors for more than 7 days within the past month, or any chemotherapy or radiation therapy within the past 3 months (emergency radiation to relieve airway blockage may be an exception — confirm with trial site)
  • People with serious other health conditions or mental health conditions that could affect their safety, ability to follow the study requirements, or the reliability of the results — the trial team assesses these situations individually with the lead researcher
  • People with severe malnutrition, an active serious infection, heart failure, or who are unable to tolerate chemotherapy treatment

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Xiaofan Zhu, MD, Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC

Phone: +86 22 23909196

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Institute of Hematology & Blood Diseases Hospital, China
Registry
ClinicalTrials.gov
Start date
11 March 2025
Est. completion
1 June 2030

Where this trial is recruiting

🇨🇳 China Hong Kong

Primary endpoints

End-of-induction(EOI) measurable residual diseases (MRD)-negativity rate in patients with non-ETP T-ALL treated with dasatinib plus 4-drug induction compared to those treated with 4-drug induction in CCCG-ALL-2020; For non-ETP T-ALL patients with positive measurable residual diseases (MRD) on day 46, to compare MRD-negativity rate before consolidation between those receiving single agent homoharringtonine at dose of 1mg/m2 vs. 2mg/m2 for 7 days; End of induction (EOI) measurable residual diseases (MRD)-negativity rate with venetoclax plus 3-drug induction, compared to those treated with 4-drug...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov