Prostate Cancer Trial, Recruiting NCT06862856 Sponsor: Massachusetts General Hospital Condition: Prostate Cancer
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Prostate Cancer Trial, Recruiting

NCT06862856
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with prostate cancer (specifically adenocarcinoma) confirmed by biopsy, and who have already had their prostate surgically removed (radical prostatectomy) as a curative treatment.
  • People who have a detectable but very low PSA level after surgery (above zero but no higher than 0.20 ng/mL), suggesting the cancer may have returned or persisted, with that PSA result taken within the last 60 days.
  • People who are at least 6 weeks past their prostate removal surgery, and if hormone-blocking therapy was previously used, it must have been stopped at least 16 weeks before the scheduled scan.
  • People who have been prescribed a specific type of imaging scan called a flotufolastat F 18 PSMA PET/CT as part of their regular medical care.
  • People aged 18 or older.
  • People who have had or currently have another type of cancer, as long as that cancer or its treatment is not expected to affect the safety or results of this trial (confirm with trial site).
  • People who are able to understand the trial and are willing to sign a consent form.

Who may not be able to join:

  • People who are currently receiving hormone-blocking therapy for prostate cancer, including surgical removal of the testicles, hormone injections or implants, or anti-androgen medications (either alone or in combination).
  • People who are currently taking part in another clinical trial using an experimental treatment for prostate cancer, where that treatment was taken within a specific recent time window before the scan (confirm with trial site).
  • People who have had an allergic reaction to flotufolastat F 18 or to chemically similar substances used in this study.
  • People who have received an X-ray contrast dye within 24 hours before the scan, or another PET imaging agent within 24 hours (or longer, depending on the agent) before the scan.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Jason Efstathiou, MD, DPhil, Massachusetts General Hospital

Phone: 617-726-5866

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
20 May 2025
Est. completion
16 January 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Detection Rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov