Phase 2 Vasculitis Trial, Recruiting NCT06868290 Sponsor: Novartis Pharmaceuticals Condition: Vasculitis
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Phase 2 Vasculitis Trial, Recruiting

NCT06868290
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults between 18 and 75 years old who have been diagnosed with a condition called GPA (Granulomatosis with Polyangiitis) or MPA (Microscopic Polyangiitis), based on recognised 2022 medical classification guidelines
  • People who have tested positive for specific proteins in their blood called ANCA antibodies
  • People with GPA or MPA whose disease is currently severe and active

Who may not be able to join:

  • People who have a condition that would make it impossible to safely clear certain medications from their body before the treatment, or that would otherwise make them unsuitable for this type of therapy (confirm with trial site)
  • People who have had allergic reactions to, or medical reasons to avoid, any of the medications or treatments used in this trial
  • People who have other autoimmune diseases (where the immune system attacks the body) that currently require treatment
  • People who have other health conditions — unrelated to GPA or MPA — that could make it unsafe for them to receive this type of treatment
  • People whose kidneys, liver, or other organs are not working well enough to safely take part in the trial (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Novartis Pharmaceuticals, Novartis Pharmaceuticals

Phone: 1-888-669-6682

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
13 March 2025
Est. completion
7 June 2029

Where this trial is recruiting

🇧🇷 Brazil 🇮🇱 Israel 🇯🇵 Japan 🇸🇦 Saudi Arabia 🇸🇬 Singapore 🇨🇭 Switzerland 🇬🇧 United Kingdom 🇺🇸 United States

Primary endpoints

Event-free survival (EFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov