Phase 1 Pulmonary Hypertension Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are a healthy volunteer (the trial aims for an equal number of men and women, and if you drop out, you would be replaced by someone of the same sex)
• You are between 18 and 45 years old
• If you are male, you weigh at least 50kg; if you are female, you weigh at least 45kg; and your BMI (a measure of body weight relative to height) is between 19 and 26
• You have passed a full health check-up covering things like blood tests, urine tests, heart tracing (ECG), liver and kidney function, checks for infections like hepatitis B, hepatitis C, HIV and syphilis, a chest X-ray, an abdominal scan, and tests for nicotine, drugs, and alcohol — with no significant health concerns found
• You fully understand what the trial involves, including its possible benefits and risks, and are willing to sign a consent form and follow all study requirements

Who may not be able to join:

• You have taken part in another clinical trial within the last 3 months
• Your blood test results show that your liver function markers (ALT, AST, or bilirubin) are above the normal range
• You have an existing liver condition, such as chronic hepatitis B or C, alcoholic liver disease, significant fatty liver disease, or cirrhosis (confirm with trial site)
• You have any condition affecting your heart, liver, kidneys, hormones, digestion, immune system, lungs, nerves, or mental health — including cardiovascular disease, bowel conditions that affect how you absorb medicines, active bleeding (such as stomach ulcers), epilepsy, severe allergic skin or breathing conditions, or active tuberculosis
• You have a history of allergies to any medicines, foods, or skin-related allergens
• You have taken any medicines in the 28 days before the trial that are known to affect how the liver processes drugs — including certain antibiotics, antifungals, anti-seizure medicines, steroids, or other specific drugs (confirm the full list with the trial site)

Important: Always verify eligibility with the trial site directly before applying.