Phase 2 study for people with Autosomal Dominant Polycystic Kidney Disease

Recruiting Phase 2

Sources: ClinicalTrials.gov Checked: 13 October 2026 Not medical advice

This trial at a glance

Status Recruiting
Phase Phase 2
Sponsor Calico Life Sciences LLC
Registry number NCT06902558
Started 9 June 2025 Today 16 October 2026 Estimated completion 1 August 2029

Where this trial is running

Trial sites and the status recorded for each
SiteCityState or countryStatus at this site
Westmead Hospital Westmead NSW Recruiting
Royal Brisbane and Women's Hospital Brisbane QLD Recruiting
Royal Adelaide Hospital Adelaide SA Recruiting
Fiona Stanley Hospital Murdoch WA Recruiting

voxsanity.com.au · trial sites from public registries · registry record synced 13 October 2026 · not medical advice

Who can join

Age 18 Years to 55 Years
Sex Anyone, regardless of sex
Healthy volunteers Not accepted
Enrolment target 240

The official eligibility criteria

Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.

Inclusion Criteria:

* Autosomal Dominant Polycystic Kidney Disease (ADPKD) Class 1C, 1D, or 1E based on the Mayo Clinic Imaging Classification of ADPKD.

* Estimated glomerular filtration rate (eGFR) \>= 30 mL/min/1.73 m\^2 and \< 90 mL/min/1.73 m\^2, using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation at Screening.

Exclusion Criteria:

* Current interventions to treat ADPKD such as non-approved medications or lifestyle modifications.

* Any exclusionary medical diseases, disorders, or conditions as described in the protocol.

Dates on the record

Started 9 June 2025
Estimated completion 1 August 2029
Registry last updated 6 October 2026
Checked by Voxsanity 13 October 2026

Results, publications and the official record

Sources and dates

  • ClinicalTrials.gov – the record this page reformats
  • ClinicalTrials.gov processing date: 6 October 2026.
  • This page last checked by Voxsanity: 13 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

Letter for your doctor

A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.