Phase 3 Breast Cancer Trial, Recruiting NCT06915857 Sponsor: Sunnybrook Health Sciences Centre Condition: Breast Cancer
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Phase 3 Breast Cancer Trial, Recruiting

NCT06915857
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are 18 years of age or older
  • People who are female
  • People who have been diagnosed with breast cancer (either invasive or in situ) or a phyllodes tumour, confirmed by a tissue sample test
  • People who have larger breasts (bra size 40 or above and/or D cup or larger) and have already had breast-conserving surgery (surgery that removes the tumour but keeps most of the breast)
  • People who are scheduled to receive one of three types of radiation treatment to the whole or part of the breast, delivered while lying face-down
  • People who are receiving radiation treatment with or without an additional targeted boost dose
  • People who speak English, or who are able to participate with the help of a translator

Who may not be able to join:

  • People who are planned to receive a type of internal radiation treatment (brachytherapy) in the treatment area, or who are scheduled to receive radiation to both breasts
  • People who have previously had radiation treatment to any part of the area now being planned for treatment
  • People who currently have a rash or an existing skin condition in the area planned for treatment
  • People who are receiving certain chemotherapy medicines at the same time as radiation treatment
  • People who are unable to lie face-down for radiation treatment
  • People whose treatment plan involves placing a special material on the skin to adjust the radiation dose (called tissue equivalent bolus)
  • People who have a known sensitivity or allergy to a medicine called betamethasone
  • People who are known to be pregnant

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Edward LW Chow, MBBS, Sunnybrook Health Sciences Centre

Phone: 416-480-4974

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Registry
ClinicalTrials.gov
Start date
26 February 2025
Est. completion
6 September 2026

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Acute grade 2 or 3 toxicities as defined by the CTCAE v5.0 assessed by HCP

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov