Osteoarthritis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have painful knee osteoarthritis and need a first-time total knee replacement surgery
• People whose surgeon agrees that a total knee replacement is the most suitable treatment for their condition
• People who have been assessed by a surgeon and anaesthetist and are considered medically safe to have surgery
• People who are over 18 years old at the time of surgery
• People of any gender (male or female)
• People who are able to understand the study, give their consent, and are willing to follow the post-surgery review schedule
• People who are mobile enough after surgery to attend follow-up appointments and have X-rays taken

Who may not be able to join:

• People whose condition is too complex for a standard first-time knee replacement — for example, if ligament damage means a more specialised implant is needed
• People who have significant bone loss that would require bone grafting or bone-building procedures during surgery
• People who are not considered medically safe to have surgery
• People who need a repeat knee replacement after a previous knee replacement or a bone-correcting surgery on the same leg has failed
• People who have a bone density scan result showing a T-score below -2.5, indicating significant bone thinning (confirm with trial site)
• People who are unable to walk independently, or who have a neurological condition that affects how their muscles and bones work
• People who are under 18 years old at the time of surgery
• People who are unable or unwilling to sign the study's consent form
• People who are unable to attend the required follow-up appointments
• People who have previously had a fracture caused by a bone disease or condition

Important: Always verify eligibility with the trial site directly before applying.