Phase 1 Eczema Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
For Parts A, B, and C (earlier study phases):
- Men and women between 18 and 45 years old (inclusive)
- Men weighing at least 50 kg (about 110 lbs) and women weighing at least 45 kg (about 99 lbs), with a body mass index (BMI) between 18.0 and 30.0
For Part D (later study phase):
- Men and women between 18 and 75 years old
- People who have had a confirmed diagnosis of chronic eczema (atopic dermatitis) for at least 6 months before the screening visit
- People whose eczema is considered moderate to severe based on specific medical scoring systems at the time of screening (confirm with trial site)
- People who have experienced significant itching on most days in the week before their first dose (confirm with trial site)
- People whose eczema did not improve enough with skin-applied (topical) treatments within the 6 months before screening
Who may not be able to join:
- People with significant health conditions affecting the nervous system, heart, lungs, digestive system, kidneys, immune system, or other major body systems, as assessed by the study doctor
- People whose heart electrical activity reading (ECG) shows an abnormal result above a certain level at screening (confirm with trial site)
- People who smoke more than 5 cigarettes a day on average, or who currently use e-cigarettes
- People who drink more than 14 units of alcohol per week (roughly 14 small glasses of wine or beers), or who test positive for alcohol at screening
- People who have donated more than 400 mL of blood in the 3 months before screening, or more than 200 mL in the 4 weeks before screening, or who plan to donate blood during the study
- People who have taken certain strong medications that affect how the body processes drugs (CYP3A4 inhibitors or inducers) within 4 weeks before screening (confirm with trial site)
- People who have taken any prescription medicines, over-the-counter drugs, herbal remedies, or dietary supplements within 2 weeks before their first dose (or longer, depending on the medication)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: (+86) 18600489179
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Incidence and severity of treatment emergent Adverse Events as assessed by CTCAE v5.0
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.