COPD Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults over 18 years of age
• People who have been diagnosed with moderate to very severe COPD (classified as GOLD stage II, III, or IV)
• People who have already completed a pulmonary rehabilitation program at the trial site
• People whose 6-minute walk test result was less than 350 meters, either before or after completing pulmonary rehabilitation
• People who experience significant breathlessness in daily life, rated at level 2 or higher on a standard breathlessness scale
• People whose lungs trap an excessive amount of air (a condition called pulmonary hyperinflation, confirmed by specific lung volume measurements)
• People who use supplemental oxygen or those who do not
• People whose condition has been stable for at least the last 4 weeks, with no flare-ups or changes to their treatment
• People who have never previously received a treatment called intermittent intrapulmonary deflation
• People who are affiliated with social security and have read, understood, and signed the study consent form

Who may not be able to join:

• People who are pregnant or may become pregnant
• People who are under legal guardianship or a similar protected legal arrangement
• People who are unable to give their own informed consent
• People whose primary lung diagnosis is a condition other than COPD, such as asthma or primary bronchiectasis
• People who have bone, nerve, blood vessel, or muscle conditions that affect their ability to walk, or who require a walking aid
• People with serious or unstable heart conditions, such as uncontrolled irregular heartbeat, severe heart failure, a recent heart attack, or unstable chest pain
• People who currently need assisted breathing through a tube, mask, or breathing machine, or who have a condition causing weakness in the breathing muscles, or who cannot cough strongly on their own
• People whose circulation or blood pressure is currently unstable
• People who have had a collapsed lung (pneumothorax) within the last 3 months
• People who have had surgery on their lungs or upper airways within the last month
• People who have been referred to pulmonary rehabilitation as preparation for chest surgery, such as lung volume reduction, lung transplant, or lung cancer surgery
• People who are using or plan to use an electrical or mechanical airway clearance device during the study period (such as a cough assist machine or chest oscillation vest)
• People with an active cancer diagnosis
• People who have had a severe episode of coughing up blood within the last 3 months
• People who have a severe condition causing the windpipe to collapse (severe tracheomalacia)
• People who withdraw their consent after joining
• People who experience a COPD flare-up or develop heart or breathing instability between study visits

Important: Always verify eligibility with the trial site directly before applying.