Osteoarthritis Trial, Recruiting NCT06960564 Sponsor: Istanbul University Condition: Osteoarthritis
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Osteoarthritis Trial, Recruiting

NCT06960564
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with knee osteoarthritis (knee joint wear and tear) based on standard medical guidelines
  • You have had knee pain for more than 3 months
  • Your knee pain has not improved with standard treatments (such as physiotherapy or pain medication) for at least 3 months
  • You are between 45 and 75 years old
  • Your knee X-rays show a moderate level of joint damage (classified as stage 2 or 3 on a standard medical scale)

Who may not be able to join:

  • Your knee joint damage is classified as very mild (stage 1) or very severe (stage 4) on X-ray
  • You have serious conditions affecting other parts of your body, such as severe heart, kidney, or liver disease, uncontrolled diabetes, cancer, a weakened immune system, blood disorders, or bone diseases affecting the whole body
  • You have a tendency to bleed easily, whether due to a medical condition or a blood-thinning medication (confirm with trial site)
  • You currently have an infection anywhere in your body, or specifically in or near the knee
  • Your knee osteoarthritis was caused by another condition, such as an inflammatory joint disease, a past injury, or a previous infection
  • You have had a significant knee injury within the last year
  • Your Body Mass Index (BMI — a measure of body weight relative to height) is over 40
  • You have had a full knee or hip replacement surgery within the last year
  • You are pregnant
  • You have had an injection into a joint within the last 6 months
  • Your blood test results show that your haemoglobin (a measure of red blood cells) or platelet levels (cells that help blood clot) are below certain levels (confirm with trial site)
  • You are allergic to hyaluronic acid products (a substance sometimes injected into joints)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 2 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Istanbul University
Registry
ClinicalTrials.gov
Start date
12 May 2025
Est. completion
30 January 2026

Where this trial is recruiting

Turkey (Türkiye)

Primary endpoints

Blood and synovial fluid TNF-alpha levels; Blood and synovial fluid IL-1beta levels; Blood and synovial fluid TNF-alpha methylation changes; Blood and synovial fluid IL-1beta methylation changes

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 2 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov