Alzheimer's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have been diagnosed with mild-to-moderate Alzheimer's disease based on recognised medical guidelines
- You scored between 10 and 22 on a standard memory and thinking test called the MMSE
- Both you and your caregiver can understand and communicate in English or Mandarin
- You are able to give your own consent to participate, or you have a trusted legal representative who can do this on your behalf
- You have good support from family members to help with your care and recovery after the procedure
- You are considered healthy enough to safely undergo general anaesthesia or deep sedation and surgery (not counting the Alzheimer's diagnosis itself)
Who may not be able to join:
- Your memory or thinking problems are caused by a past infection or an autoimmune disease rather than Alzheimer's disease
- You have had a significant stroke or serious heart or blood vessel disease
- Your head cannot be gently turned at least 40 degrees to the side
- You have had previous surgery or radiation treatment on the lymph nodes in your neck
- You currently have an active infection or cancer
- You have any medical reason that would make surgery or a lumbar puncture (spinal fluid sample) unsafe for you
- You have a reason you cannot safely have an MRI or PET scan, such as a non-MRI-safe metal implant in your body or a known allergy to the scan tracers used
- You have taken part in an experimental Alzheimer's treatment within the last 6 months
- You are currently being treated with monoclonal antibody medications such as lecanemab or donanemab
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: +65 6788 8833
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Safety: Number of treatment-related adverse events; Mini Mental State Examination; Montreal Cognitive Assessment; Clinical Dementia Rating (CDR); Neuropsychiatric Inventory (NPI); Geriatric Depression Scale-Short Form (GDS-SF); Quality of Life - Alzheimer's Disease (QoL-AD); Zarit Burden Score; Basic and instrumental Activities of Daily Living; Basic Gait Assessment
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.