Phase 2 Breast Cancer Trial, Recruiting NCT06974929 Sponsor: Jiangsu HengRui Medicine Co., Ltd. Condition: Breast Cancer
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Phase 2 Breast Cancer Trial, Recruiting

NCT06974929
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Women between 18 and 75 years of age
  • People whose general health and ability to carry out daily activities meets a specific medical standard (known as ECOG performance status 0–1 — confirm with trial site for what this means in practice)
  • People whose menopausal status meets the trial's requirements (confirm specific menopausal criteria with trial site)
  • People whose cancer has shown signs of getting worse on scans during or after their most recent cancer treatment
  • People who have at least one area of cancer that can be measured on a scan, located outside the brain, meeting specific size and imaging standards
  • People whose expected survival is greater than 3 months, as assessed by the treating doctor
  • Women who could become pregnant must agree to use highly effective contraception during treatment and for 6 months after treatment ends, must have a negative pregnancy blood test within 7 days before joining, and must not be breastfeeding
  • People who are willing and able to attend all study visits and follow study procedures, and who have signed a consent form agreeing to take part

Who may not be able to join:

  • People who have cancer that has spread to internal organs in a way that is causing symptoms, where the treating doctor judges that hormone-based therapy would not be appropriate
  • People with a history of serious heart or blood vessel disease
  • People whose heart trace (ECG) results show abnormalities
  • People with clinically significant abnormalities of the uterine lining, including conditions such as endometrial hyperplasia or abnormal uterine bleeding
  • People who have an active infection or active tuberculosis requiring medication at the time of joining
  • People who have had surgery, chemotherapy, immunotherapy, or certain targeted treatments within 4 weeks before starting the trial
  • Women who are pregnant, breastfeeding, or planning to become pregnant during the study
  • People with a known history of significant neurological or psychiatric conditions, or a history of misusing psychotropic substances or drugs
  • People who are expected to need other cancer treatments or medications during the course of this trial

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: +86-0518-82342973

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Registry
ClinicalTrials.gov
Start date
22 May 2025
Est. completion
1 December 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Dose-limiting toxicity (DLT); Maximum tolerated dose (MTD); Recommended phase II dose (RP2D); Adverse events (AEs); Serious adverse events (SAEs); Objective response rate (ORR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov