Phase 3 Psoriasis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have had stable plaque psoriasis for 6 months or longer before the screening visit.
- Your psoriasis is rated as moderate to severe based on three measurements taken at your screening visit and first study day: a skin scoring system called PASI (score of 12 or higher), a doctor's overall rating of your skin (score of 3 or higher), and psoriasis covering at least 10% of your body surface area.
- If you were born female, you are eligible if you are not pregnant or breastfeeding, and either cannot become pregnant, or are using a highly effective form of contraception during the study and for at least 3 days after finishing the study treatment, and agree not to donate eggs during that same period.
Who may not be able to join:
- You weigh less than 30 kg (about 66 lbs) at the time of screening or on the first study day.
- You have a type of psoriasis other than plaque psoriasis (such as guttate, pustular, or others), or another skin condition that could affect how your skin is assessed during the study.
- You were hospitalised for a serious bacterial, fungal, or viral infection requiring IV antibiotics or antiviral treatment within the past 60 days.
- You have had any untreated bacterial infection within the past 60 days.
- You have an ongoing long-term bacterial infection, such as chronic kidney, bone, or lung infections.
- You have active herpes, active tuberculosis, hepatitis B, hepatitis C, or HIV infection (confirm with trial site for full details).
- You have received a live vaccine or BCG vaccine within the past 60 days, or plan to receive one during the study or within 60 days of finishing the study treatment.
- You have previously taken the drug deucravacitinib.
- You are currently taking certain medications that are not allowed in this trial (confirm with trial site for the full list).
- You have abnormal laboratory test results that meet the study's exclusion criteria (confirm with trial site for specifics).
- You have a serious or unstable health condition affecting organs such as the kidneys, liver, lungs, heart, or nervous system, or have an active infection that the study doctor believes would put you at significant risk.
- You have been diagnosed with cancer or a blood/lymph system disease within the past 5 years.
- There may be additional eligibility requirements not listed here (confirm with trial site).
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Bristol-Myers Squibb, Bristol-Myers Squibb
Phone: 855-907-3286
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Number of participants achieving at least 75% improvement in Psoriasis Area and Severity Index (PASI 75); Number of participants achieving a static Physicians Global Assessment (sPGA) score of 0 (clear) or 1 (almost clear) with at least a 2-point reduction from baseline
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.