Phase 2 Macular Degeneration Trial, Recruiting NCT06990269 Sponsor: ADARx Pharmaceuticals, Inc. Condition: Macular Degeneration
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Phase 2 Macular Degeneration Trial, Recruiting

NCT06990269
Recruiting Phase 2 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with geographic atrophy (a type of vision loss affecting the central part of the eye) caused by age-related macular degeneration (AMD)
  • People whose affected area in the eye falls within a specific size range, as measured at the screening visit
  • People whose eye is clear enough, and who can keep their gaze steady enough, to allow good-quality imaging of the back of the eye
  • People who are willing and able to attend clinic visits and follow study procedures, including completing a required series of vaccines for meningococcal and pneumococcal diseases

Who may not be able to join:

  • People whose geographic atrophy is caused by something other than AMD
  • People who have another active eye disease that affects their vision
  • People who have had surgery for a detached retina
  • People who have another eye condition in addition to geographic atrophy caused by AMD
  • People who have received certain eye injections that affect the complement system (a part of the immune system) in the eye being studied
  • People who have an inherited or acquired deficiency affecting their complement system
  • People who currently have an active viral, bacterial, or fungal infection
  • People who have signs of liver damage, as shown by abnormal liver blood test results
  • People who donate blood
  • People who have a history of abnormal blood vessel growth under the retina in the eye being studied

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Aditya Patel, MD, ADARx Pharmaceuticals, Inc.

Phone: 877-232-7974

Australian sites

ADARx Clinical Site, Albury, New South Wales
ADARx Clinical Site, Hurstville, New South Wales
ADARx Clinical Site, Parramatta, New South Wales
ADARx Clinical Site, East Melbourne, Victoria
ADARx Clinical Site, Rowville, Victoria

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
ADARx Pharmaceuticals, Inc.
Registry
ClinicalTrials.gov
Start date
10 November 2025
Est. completion
28 February 2030

Where this trial is recruiting

🇦🇺 Australia 🇨🇦 Canada 🇺🇸 United States

5 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Evaluate the effect of ADX-038 on the preservation of the EZ layer

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov