Glaucoma Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 years or older
• People who have been diagnosed with primary open-angle glaucoma (a common type of glaucoma where fluid drainage in the eye is reduced), or people with no history of glaucoma (who would participate as a comparison group)
• People whose eye examination shows an open drainage angle in the eye (a specific measurement called Shaffer grade 3 or 4)
• People whose vision, when corrected with glasses or contact lenses, is 20/25 or better
• People whose prescription falls within a moderate range — between +3.00 and -5.00 diopters (not too far-sighted or too short-sighted)
• People who have never previously used eye drop medications for glaucoma
• People diagnosed with high-pressure glaucoma (eye pressure of 22 mmHg or higher recorded on 3 visits), normal-pressure glaucoma (eye pressure of 21 mmHg or lower recorded on 3 visits), or people with a healthy optic nerve and normal visual fields who are a similar age to those with glaucoma (comparison group)

Who may not be able to join:

• People with corneal (front surface of the eye) problems that could interfere with certain pressure-measurement tests used in the trial
• People with retinal diseases that affect the nerve fibre layer of the eye (for example, conditions causing pulling or traction on the central part of the retina)
• People who have had any previous eye surgery or laser treatment to the eye
• People who have been diagnosed with diabetes
• People with a history of uveitis (inflammation inside the eye)
• People who have used steroid medications (such as cortisone or prednisone) for a long period of time
• People with neurological or other whole-body conditions such as multiple sclerosis, Alzheimer's disease, Parkinson's disease, or schizophrenia
• People whose visual field test results are considered unreliable
• People who have medical reasons why they cannot take a type of medication called beta blockers — for example, a very slow heart rate or severe lung disease
• People with moderate to severe glaucoma, based on a specific grading system used by eye specialists (Hodapp-Anderson-Parrish criteria)
• People who have a history of wearing contact lenses
• People with low blood pressure

Important: Always verify eligibility with the trial site directly before applying.