Phase 1 Ovarian Cancer Trial, Recruiting NCT06997029 Sponsor: Bristol-Myers Squibb Condition: Ovarian Cancer
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Phase 1 Ovarian Cancer Trial, Recruiting

NCT06997029
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must be 18 years of age or older.
  • You must have a confirmed diagnosis of a solid tumor cancer that has spread, cannot be surgically removed, or is locally advanced.
  • Your cancer must have at least one area that can be measured on a scan, according to standard medical guidelines.
  • You must be in generally good physical condition and able to carry out normal daily activities with little or no limitation (confirm with trial site).
  • For one specific part of the trial (Part 2A only): you must have ovarian cancer with a specific genetic change called CCNE1 amplification (confirm with trial site).

Who may not be able to join:

  • You may not be eligible if your cancer has actively spread to the brain.
  • You may not be eligible if you have significant heart problems or reduced heart function.
  • You may not be eligible if you have a bleeding disorder or have had a serious bleeding episode in the past 3 months.
  • You may not be eligible if you have moderate or severe nerve damage causing symptoms such as numbness, tingling, or pain in your hands or feet.
  • There are additional eligibility requirements not listed here that the trial team will review with you.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Bristol-Myers Squibb, Bristol-Myers Squibb

Phone: 855-907-3286

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Registry
ClinicalTrials.gov
Start date
1 August 2025
Est. completion
14 December 2028

Where this trial is recruiting

🇩🇰 Denmark 🇯🇵 Japan 🇺🇸 United States

Primary endpoints

Number of Participants With Dose Limiting Toxicities (DLTs); Number of Participants With Adverse Events (AEs); Number of Participants With Serious Adverse Events (SAEs); Number of Participants With AEs Leading to Discontinuation; Number of Participants With TEAEs Leading to Death

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov