Phase 2 Prostate Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 or older.
• People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed by a tissue sample test.
• People whose prostate cancer has been classified as high risk or very high risk based on standard medical guidelines — this includes certain tumour grades, a PSA level above 20, or specific findings on an MRI scan.
• People with a testosterone level of 300 or above.
• People who are reasonably active and able to care for themselves, based on a standard medical fitness scale (confirm with trial site).
• People with blood test results within acceptable ranges — including red blood cell levels, infection-fighting white blood cells, and clotting cells — taken within the past 120 days.
• People who agree to use a condom during sex while on the study medication and for 30 days after the last dose.
• People who agree not to donate semen during treatment and for 30 days after the last dose.
• People with female partners who could become pregnant, where either a vasectomy is documented, or a commitment to abstinence or effective contraception is made, for the duration of treatment and 30 days after the last dose.
• People who are willing and able to provide written consent to participate.

Who may not be able to join:

• People who have received chemotherapy within the past 2 weeks before joining the trial.
• People who have previously received hormone therapy to reduce androgen (male hormone) levels.
• People who have previously received radiation treatment to the pelvic area.
• People with serious ongoing health conditions that, in the treating doctor's judgement, would make participation unsafe or affect the accuracy of results.
• People with uncontrolled health problems such as an active infection, heart failure with symptoms, unstable chest pain, irregular heart rhythm, or mental health or personal circumstances that could make it difficult to follow the study requirements.
• People currently taking part in another clinical trial that involves a treatment for their prostate cancer.
• People who have had another active cancer within the past year — with the exception of certain non-melanoma skin cancers — or who are currently receiving treatment for a prior cancer.
• People who have had a heart attack within the past 6 months, or who have heart failure requiring ongoing treatment for serious heart rhythm problems.
• People currently taking a type of medication known as a P-glycoprotein inhibitor (confirm with trial site for specific medicines that fall into this category).

Important: Always verify eligibility with the trial site directly before applying.