Stroke Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults aged 18 or older
• People who were largely independent before their stroke (little to no disability beforehand)
• People whose stroke symptoms started within 24 hours of when they were last known to be well
• People with a stroke severity score of 6 or higher on a standard medical scale (indicating a moderate to severe stroke)
• People whose brain scan shows a sufficient amount of healthy brain tissue remaining (meeting specific score thresholds for either the front or back areas of the brain)
• People who have a confirmed blockage in one of several specific brain or neck arteries (the internal carotid artery, a major branch of the middle cerebral artery, a vertebral artery segment, or the basilar artery)
• People whose medical team has already planned a procedure to physically remove the blood clot (called endovascular thrombectomy)
• People (or their legal representative) who are able to give informed consent to participate
• People who, after the clot removal procedure, have a significant narrowing (50% or more) remaining in the artery, and for whom no further procedure to widen the artery is planned

Who may not be able to join:

• People who have bleeding in the brain confirmed by imaging before the trial begins, or significant bleeding found during the procedure
• People who have had bleeding in the stomach, intestines, or urinary tract within 30 days of the stroke, or who have had major surgery within the past 14 days
• People with blood clotting problems — including low platelet counts, abnormal clotting test results, use of certain blood-thinning medications within the past 48 hours, or a history of a specific reaction to a blood-thinning drug called heparin
• People who are pregnant or breastfeeding at the time of admission
• People with known allergies or sensitivities to contrast dye used in imaging, or to nickel, titanium, or their alloys
• People with a life expectancy of less than 6 months
• People with pre-existing neurological or psychiatric conditions that could make it difficult to assess the effects of the trial (confirm with trial site)
• People with severely reduced kidney function
• People whose artery shape or structure would make it physically impossible to deliver the trial device
• People who are unlikely to be available for a follow-up assessment at 90 days
• People whose stroke is confirmed to have come from a heart-related source, such as an irregular heart rhythm (atrial fibrillation), heart valve disease, a clot inside the heart, a recent heart attack, or a weakened heart muscle
• People who received certain blood-thinning medications (tirofiban or similar drugs called GP IIb/IIIa inhibitors) before being enrolled in the trial, or who received a different one of these medications after treatment

Important: Always verify eligibility with the trial site directly before applying.