Phase 4 Breast Cancer Trial, Recruiting NCT07042581 Sponsor: Memorial Sloan Kettering Cancer Center Condition: Breast Cancer
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Phase 4 Breast Cancer Trial, Recruiting

NCT07042581
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are 18 years of age or older at the time of signing the consent form
  • People who have been diagnosed with Stage 0 to Stage 3 hormone-receptor positive breast cancer, confirmed at MSKCC
  • People who are able to complete study questionnaires in English or Spanish
  • People who have finished their main breast cancer treatments (such as surgery, chemotherapy, or radiation therapy), or who are currently on ongoing maintenance treatment
  • People who are currently taking an aromatase inhibitor, tamoxifen, or a similar type of medication (called a SERM)
  • People who currently have no signs of active cancer
  • People who are experiencing vaginal symptoms linked to low estrogen, such as vaginal dryness, pain during intercourse, or discomfort during a medical examination
  • People whose vaginal symptom score reaches 4 or higher on a specific rating scale used in the study (confirm with trial site)
  • People with no history of other cancers, apart from a common type of skin cancer called non-melanoma skin cancer
  • People who are willing to sign a consent form showing they understand the study and agree to take part

Who may not be able to join:

  • People who are not able to give informed consent
  • People who have had vaginal bleeding with no known cause within the past 12 months
  • People who are currently using hormone replacement therapy, either applied locally or taken throughout the body (a 4-week stop period may be required before the trial site can consider enrolment)
  • People who are currently using external estrogen products or non-hormonal vaginal moisturisers (a 4-week stop period may be required before the trial site can consider enrolment)
  • People who have a known allergy to any ingredient in the study treatment, a 10mg hyaluronic acid suppository

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: Shari Goldfarb, MD, Memorial Sloan Kettering Cancer Center

Phone: 646-888-5080

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Registry
ClinicalTrials.gov
Start date
20 June 2025
Est. completion
20 June 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in Vaginal Assessment Scale from baseline to 8 weeks

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov