Crohn's Disease and Colitis Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

For all participants:

• People aged 18 or older
• People who are willing and able to give their informed consent to participate
• People who generally have at least one bowel movement every 48 hours

For people with ulcerative colitis (UC):

• People who have been diagnosed with ulcerative colitis, confirmed through standard clinical, imaging, or tissue-sample testing before the screening stage
• People whose ulcerative colitis is moderately to severely active, as shown by an intestinal ultrasound measurement, and who are starting or changing their treatment because their current treatment is not working
• People who are starting or adjusting a colitis treatment (this may include certain anti-inflammatory tablets, steroids, immune-suppressing medicines, or newer biological or targeted treatments)

For people with colorectal cancer (CRC):

• People diagnosed with a colorectal cancer (a type of bowel cancer) that is not blocking the bowel and has not spread extensively to nearby tissues
• People who are ready for or have planned surgery to treat their colorectal cancer

Who may not be able to join:

For all participants:

• People with a body mass index (a measure of body weight relative to height) above 30
• People known to have a blockage, narrowing, or tightening in their digestive tract that is not caused by their current condition, which could prevent a small swallowable device from passing through (confirm with trial site)
• People who have had complex bowel surgery or recent abdominal surgery within the last 3 months
• People known to have scar tissue inside the abdomen that causes organs or tissues to stick together
• People who have difficulty swallowing, including certain specific swallowing conditions
• People who currently have an active infection
• People who are known to be pregnant, breastfeeding, or actively trying to become pregnant (based on self-reporting)
• People with short bowel syndrome or who have a stoma (an opening in the abdomen for waste)
• People who receive all their nutrition through a drip into the bloodstream rather than by eating or drinking
• People who have a pacemaker or any other electronic device implanted in their body
• People who have an MRI scan planned during the period when the swallowable measurement device would be in use
• People who are not willing to have an X-ray if it is needed to confirm that the swallowable device has left the body
• People who are currently taking part in another medical research study
• People who work during the trial period in certain settings, including hospitals or clinical facilities (such as intensive care, emergency rooms, operating theatres, or patient wards), military environments (such as submarines or areas near radar equipment), or heavy industrial sites (such as power plants, mines, or refineries)

For people with colorectal cancer (CRC):

• People who have been diagnosed with, or are strongly suspected to have, inflammatory bowel disease (IBD)
• People who are planned to receive chemotherapy or radiotherapy as part of their cancer treatment

For people with ulcerative colitis (UC):

• People who have been diagnosed with, or are strongly suspected to have, colorectal cancer
• People who are using rectal foam or enema treatments during the measurement period of the trial

Important: Always verify eligibility with the trial site directly before applying.