Polymyalgia Rheumatica Trial, Recruiting NCT07060274 Sponsor: Centre Hospitalier le Mans Condition: Polymyalgia Rheumatica
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Polymyalgia Rheumatica Trial, Recruiting

NCT07060274
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 50 or older
  • People who are not under any form of legal guardianship or protection
  • People who have been diagnosed with Giant Cell Arteritis (GCA) according to the 2022 ACR classification criteria, and who also have a specific finding called a "halo sign" — seen on one or both sides — during an ultrasound scan of the temporal artery (a blood vessel near the temple)
  • People who have been newly diagnosed and for whom doctors have determined that steroid (corticosteroid) treatment is needed
  • People who have not yet started any steroid treatment for GCA
  • People for whom steroid treatment is not medically ruled out
  • People who are enrolled in, or covered by, a social security or health insurance scheme
  • People who have given their free, fully informed, and written consent before any research-related examinations take place

Who may not be able to join:

  • People who are experiencing a relapse (return) of Giant Cell Arteritis, rather than a new diagnosis
  • People who have previously had a temporal artery biopsy (a small tissue sample taken from the artery near the temple), for any reason
  • People who have taken oral steroid medication in the past month, or who are currently on steroid therapy (note: hydrocortisone and locally applied steroids are excluded from this restriction — confirm with trial site)
  • People who have another type of blood vessel inflammation (vasculitis) that could explain their symptoms, indicated by certain positive blood or laboratory tests (ANCA antibodies, syphilis serology, or a positive IGRA test)
  • People who have received immunosuppressive treatments or biologic therapies (medicines that target the immune system) within the month before joining the trial

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +332 44 71 07 81

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Centre Hospitalier le Mans
Registry
ClinicalTrials.gov
Start date
27 February 2026
Est. completion
1 February 2028

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Number of patients with GCA AND temporal artery Doppler WITH a halo sign on Day 0 of corticosteroid therapy and disappearing on Day 3.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov