Phase 2 Prostate Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma), confirmed by a laboratory tissue test
• People who are generally healthy and active, or have only mild limitations in daily activity (this is measured by a standard medical scale called ECOG 0–1)
• People with a life expectancy of at least 12 weeks
• People whose blood test results show white blood cell counts, platelet counts, and haemoglobin levels within the required ranges (confirm with trial site for exact values)
• People whose kidney and liver function blood tests fall within the required ranges (confirm with trial site for exact values)
• People who are able to produce sperm must be willing to use effective contraception during the trial
• People who are willing to provide blood samples for research purposes
• People who are able to complete questionnaires, either on their own or with help
• People who are able to undergo a procedure called leukapheresis, where blood is drawn to collect certain blood cells
• People who do not have a known immune system deficiency
• People who have not had another type of cancer in the past 5 years, except for certain skin cancers (basal cell or squamous cell) that were treated with local surgical removal only
• People who do not have another serious illness at the time of joining
• People who have no known history of a positive tuberculosis (PPD) skin test
• People whose HIV and Hepatitis C virus (HCV) tests have come back negative

Who may not be able to join:

• People who were still taking a steroid medication called dexamethasone at a dose greater than 4 mg per day at the time of a specific blood cell collection procedure
• People who have a history of autoimmune diseases, or any condition that requires long-term use of hormonal or immune-suppressing medications
• People who have a history of allergic reactions to immune cells or to the supporting substances used in cell-based treatments
• People who have an active infection with a fever at the time of joining
• People who have had a prolonged low white blood cell count (lasting more than 10 days) that has been difficult to correct with treatment
• People with a bacterial, fungal, or viral infection that is not under control
• People who are living with HIV, active Hepatitis B (HBV), or active Hepatitis C (HCV)
• People who have severe failure of a major organ, such as the heart, liver, kidneys, or lungs
• People who have previously received a cell therapy treatment and have been assessed by the trial team as not suitable for this type of treatment
• People who, in the opinion of the researchers, have any other factor that could increase risk or affect the reliability of the trial results (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.