Lymphoma Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults aged 18 or older, of any gender
• People who are able to understand the study and are willing to sign a written consent form
• People with a performance status score of 0–3 on the ECOG scale, which measures how much a condition affects daily activity (confirm with trial site)
• People whose doctors expect them to live for more than 3 months
• People who have been diagnosed with peripheral T-cell lymphoma (PTCL) confirmed by tissue or cell testing, using the 2022 World Health Organization classification system
• People who have at least one measurable area of lymphoma that is large enough to be detected on a PET/CT scan (short diameter of 15mm or more)
• People whose PTCL has come back or stopped responding to treatment, who have already been through at least one previous treatment, and who have never been treated with the drugs chidamide, lenalidomide, or bendamustine
• People whose side effects from previous treatments have mostly resolved — all non-hair-loss side effects must have settled to a mild level (Grade 1 or lower) before joining
• People whose heart, liver, kidneys, and lungs are functioning at an adequate level as measured by specific tests (confirm with trial site for exact values)
• People whose bone marrow is producing enough blood cells, based on blood test results meeting specific minimum levels (confirm with trial site for exact values)
• People who are willing to use contraception throughout the study and follow-up period if there is any possibility of pregnancy
• People who are likely to follow the study plan and attend all required visits

Who may not be able to join:

• People whose lymphoma has returned or stopped responding to treatment and who have previously been treated with chidamide, lenalidomide, or bendamustine, or who have had any other cancer treatment within the past 4 weeks
• People who have been enrolled in another clinical trial within the past 4 weeks
• People who have HIV infection, or active hepatitis B or C
• People who have an active infection that is not under control
• People with severe liver or kidney problems, based on specific blood test results (confirm with trial site)
• People who have a serious heart condition or severe irregular heartbeat that is causing symptoms or affecting heart function
• People who have another cancer that currently needs treatment
• People who have a history of blood clots in their veins or arteries, either in the past or currently
• People who are pregnant or breastfeeding
• People who have severely weakened immune systems
• People with psychological conditions that would make it difficult to participate in the study or sign a consent form
• People who are unlikely to be able to complete all required study visits and procedures

Important: Always verify eligibility with the trial site directly before applying.