Alzheimer's Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with Alzheimer's disease based on specific medical guidelines (called IWG criteria)
• Your score on a standard memory and thinking test (called the MMSE) falls between 20 and 28, indicating mild to moderate difficulty
• Your brain scan or spinal fluid test has shown signs of a protein buildup linked to Alzheimer's disease (called amyloid)
• Your overall level of dementia, measured by a standard rating scale (CDR), is mild or less
• Your medical records show that your memory or thinking has been getting worse for more than six months
• You have a caregiver who lives with you or sees you regularly and is available to take part
• You live at home or in a care home that does not provide around-the-clock nursing care
• Your general health is good enough to take part in a six-month study
• Any medicines you take regularly have been the same for at least one month before the study begins
• You are not taking any medications that are not allowed in this trial
• You (and your caregiver) are willing and able to sign a consent form agreeing to take part

Who may not be able to join:

• You are unable to attend or complete the required check-up appointments at the start of the study
• You were hospitalised or had a change in your regular medicines in the month before or during the initial screening period
• You have been diagnosed with another type of dementia, such as Lewy body dementia, frontotemporal dementia, Huntington's disease, or a similar condition
• You have another brain or nervous system condition, such as Parkinson's disease or motor neurone disease (ALS)
• You have a condition causing sudden drops in blood pressure when standing (orthostatic hypotension) or problems with the body's automatic functions (confirm with trial site)
• You have had a significant stroke or have extensive damage to the white matter of the brain
• You have another serious brain condition, such as a tumour, severe head injury, or bleeding around the brain
• You have a history of epilepsy or seizures
• You have an infection, hormone problem, or other body-wide illness that affects the brain (for example, untreated low thyroid function or vitamin B12 deficiency)
• You currently have a diagnosis of severe depression, schizophrenia, or bipolar disorder
• You have a serious or unstable illness that could affect your ability to take part or be assessed safely
• You have a disability that would prevent you from completing all parts of the study, such as severe vision or hearing loss
• You regularly take strong painkiller medicines containing opioids
• You drink more than approximately one litre of beer or 500ml of wine per day, or have signs of alcohol or drug misuse
• In the opinion of the study doctor, there is any other reason you would not be suitable for the trial

Important: Always verify eligibility with the trial site directly before applying.