Phase 2 Stroke Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults between 18 and 75 years old, of any gender
• People who have been diagnosed with an acute ischemic stroke (a stroke caused by a blocked blood vessel in the brain)
• People whose stroke symptoms began no more than 72 hours ago
• People whose stroke affects the front part of the brain's blood supply (called the anterior circulation)
• People who had little to no disability before this stroke, based on a standard disability rating scale
• People whose stroke is rated as moderate in severity on a standard medical stroke scale, and who are not deeply unconscious
• People for whom the patient themselves, or their legal guardian, has signed a consent form to participate

Who may not be able to join:

• People who have had, or are planned to have, clot-dissolving treatment or a procedure to remove a clot for this stroke
• People with a history of epilepsy (unless it is a type that no longer requires medication), Parkinson's disease, Alzheimer's disease, severe depression, or other conditions the trial doctor considers would interfere with participation
• People who have any type of bleeding in or around the brain (small spots of bleeding may be considered on a case-by-case basis by the trial doctor)
• People whose brain scans show a very large area of stroke damage or a significant shift of brain structures, where the trial doctor considers surgery likely or the outlook poor
• People who have a brain tumour or a history of any cancer
• People whose liver or kidney function falls outside acceptable levels on blood tests taken during the screening period
• People with a history of serious heart or blood vessel disease that the trial doctor considers unsuitable for participation
• People with a serious active infection, such as blood poisoning, septic shock, or severe pneumonia
• People who have received high-dose steroid medication or immune-suppressing drugs within the 14 days before starting the trial drug, or during the trial
• People who have consumed more than an average of 2 standard units of alcohol per day over the past year (where 1 unit equals 200 mL of regular beer, 25 mL of spirits, or 85 mL of wine)
• Women who are pregnant or breastfeeding, or anyone unwilling to use reliable contraception throughout the study, or anyone planning to donate sperm or eggs, or planning a pregnancy during the study
• People who have taken part in another interventional clinical trial in the past 3 months, or who have previously received any cell-based therapy (other than a blood transfusion)
• People the trial doctor considers unsuitable for any other reason, including concerns about cooperation with the study or abnormal test results

Important: Always verify eligibility with the trial site directly before applying.