Breast Cancer Trial, Recruiting NCT07085442 Sponsor: University Hospitals of Derby and Burton NHS Foundation Trust Condition: Breast Cancer
Back to Breast Cancer

Breast Cancer Trial, Recruiting

NCT07085442
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People diagnosed with early-stage breast cancer (classified as cT1-2N1M0, meaning the tumour is a certain size, cancer has spread to nearby lymph nodes, but not to distant parts of the body)
  • People who have had cancer confirmed in the armpit lymph nodes through a needle biopsy or tissue sample
  • People who had 2 or fewer abnormal lymph nodes identified on imaging scans
  • People who undergo a specific type of lymph node removal procedure called a Targeted Sentinel Node Biopsy (TSNB), where both a dye/tracer method and removal of a specially marked node are used
  • People in whom 1 or 2 larger areas of cancer spread (called macrometastases) are found in the removed nodes, with at least 3 nodes removed in total
  • People whose sentinel node could not be located during surgery may still be considered eligible if at least 3 nodes were removed and 1 or 2 macrometastases were found (confirm with trial site)
  • People whose marked node was not successfully removed during surgery may still be considered eligible if at least 3 nodes were removed and 1 or 2 macrometastases were found (confirm with trial site)
  • People whose tumour turns out to be slightly larger than expected when examined after surgery (T3 on post-operative pathology) may still remain eligible

Who may not be able to join:

  • People who have received chemotherapy before surgery (neoadjuvant chemotherapy)
  • People who have previously had lymph nodes removed from the same armpit side in an earlier procedure
  • People with a larger tumour size at diagnosis (classified as cT3-4)
  • People who had 3 or more abnormal lymph nodes identified on imaging scans

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 9 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Amit Goyal, University Hospitals of Derby and Burton NHS Foundation Trust

Phone: 01332 786958

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University Hospitals of Derby and Burton NHS Foundation Trust
Registry
ClinicalTrials.gov
Start date
17 January 2025
Est. completion
1 December 2032

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Patients with ≤2 nodal macrometastases identified on histology.; Patients with ≤2 nodal macrometastases identified on histology.; Patients with ≤2 nodal macrometastases identified on histology.; Patients with ≤2 nodal macrometastases identified on histology.; Patients with ≤2 nodal macrometastases identified on histology.; Identification rate of marked node; Identification rate of marked node; Identification rate of marked node; Identification rate of marked node; Identification rate of marked node; False negative rate of targeted sentinel node biopsy; False negative rate of targeted sentinel...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 9 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov