Printed from Voxsanity (voxsanity.com.au) — NCT07094763 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.
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Stroke Trial, Recruiting
NCT07094763
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 or older
- People who meet at least one of the following: a stroke affecting the back part of the brain (posterior circulation) confirmed by MRI scan; a blocked or narrowed major blood vessel supplying the back of the brain, seen on imaging; or reduced blood flow to the back of the brain shown on a specialised blood flow scan
- People whose stroke symptoms started between 4.5 and 24 hours before joining the trial (for strokes that happened during sleep or were not witnessed, the midpoint between when the person was last known to be well and when symptoms were noticed is used as the start time)
- People with a stroke severity score greater than 3 on a standard medical scale (NIHSS)
- People whose brain scan shows limited damage, meeting a minimum score of 7 on a brain imaging scale called PC-ASPECTS
- People who were largely independent in daily life before the stroke (a score of 1 or less on a standard scale called the mRS)
- People, or their legally authorised representative, who are able to give signed consent to participate
Who may not be able to join:
- People who have a known allergy or medical reason preventing them from receiving the clot-dissolving drug tenecteplase
- People who are planned to have a procedure to physically remove, open, or support a blocked blood vessel within the next 3 months
- People whose stroke affects the front part of the brain (anterior circulation), as confirmed by imaging
- People with a history of bleeding inside the skull or brain
- People who have had a stroke, heart attack, serious head injury, or brain or spinal surgery in the past 3 months
- People with a brain tumour, an abnormal tangle of blood vessels in the brain (AVM), or a very large brain aneurysm
- People with active internal bleeding, or who have had major surgery, a serious injury, or bleeding from the digestive or urinary tract within the past 3 weeks
- People who have had a needle inserted into a major artery (in a location where pressure cannot be applied to stop bleeding) within the past week
- People suspected of having a tear in the main artery of the body (aortic dissection)
- People with significant bleeding disorders or blood-thinning medication concerns, including: use of the blood thinner warfarin with certain blood test results above set limits; use of injectable blood thinners (low-molecular-weight heparin) in the past 24 hours; use of newer oral blood-thinning tablets in the past 48 hours; or certain abnormal blood clotting test results
- People with poor platelet function or a platelet count below a set level (100×10⁹/L)
- People with very high blood pressure that does not come down with medication (above 180/110 mmHg)
- People with very low or very high blood sugar levels that are not being controlled
- People who are pregnant or breastfeeding
- People whose life expectancy is less than 3 months
- People who have taken part in another clinical trial within the past 3 months, or who are currently enrolled in another trial
- People who may not be able to attend follow-up visits (for example, those without a fixed home address or who live overseas)
- People considered unsuitable for the trial by the doctor running the trial site
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
Contact this trial
Phone: +86055162284313
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Status
Recruiting
Phase
Not Applicable
Sponsor
The First Affiliated Hospital of University of Science and Technology of China
Registry
ClinicalTrials.gov
Start date
5 November 2025
Est. completion
30 October 2027
Where this trial is recruiting
🇨🇳 China
Primary endpoints
Proportion of patients with modified Rankin Scale (mRS) score 0-1 at 90 ±14 days;
Can't join this trial?
Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.