Stroke Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People whose affected arm has a specific level of partial movement impairment, measured by a standard stroke assessment tool called the Fugl-Meyer, with a score between 22 and 50 out of 66 (confirm with trial site)
• People whose Fugl-Meyer arm score stayed roughly the same (within 3 points) between two early study visits
• People aged 18 to 80 years old
• People whose stroke was caused by a blocked blood vessel or a bleed within the brain
• People who are between 6 months and 5 years past the date of their stroke
• People whose affected arm can move at least one block in the Box & Block Test, a simple task involving moving small blocks within 60 seconds
• People who are able to sit and use the study device for 40 minutes in a row
• People who are able to follow a three-step spoken instruction, or an equivalent non-verbal instruction
• People who are willing to take part in physical exercises during the study sessions
• People who have a family member or carer available who is able to attend training and provide support during treatment sessions at the study site and at home throughout the study
• Women who are not pregnant, not breastfeeding, and not planning a pregnancy during the study period
• People who are able to give their own informed consent to participate

Who may not be able to join:

• People with severe neglect (a condition where the brain ignores one side of the body or space) that would interfere with assessments or treatment
• People with severe depression, based on a specific depression screening score (confirm with trial site)
• People who have an implanted device that is not safe for use near MRI equipment, or who have a life-sustaining device such as a pacemaker or internal defibrillator
• People with active epilepsy, people currently taking medication specifically for a seizure disorder, or people who have had any epileptic seizure in the past 5 years
• People who have received Botulinum toxin (such as Botox) injections to the affected arm in the past 3 months, or for whom such injections are planned before the 6-month study visit
• People with severe stiffness or muscle tightness in the affected arm, specifically a score of 3 or higher on a standard spasticity scale in the bicep or chest muscle
• People with a pre-existing neurological condition (such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, brain injury, or spinal cord injury) or a physical limitation that would significantly affect participation or make results harder to interpret
• People with significant vision problems — whether pre-existing or caused by the stroke — that cannot be corrected and would significantly affect participation or make results harder to interpret
• People with an unstable or serious medical condition (such as active cancer, severe heart failure, or a serious active psychiatric condition), or a life expectancy of less than 12 months
• People with a history of alcohol or illicit drug misuse in the past 6 months that is likely to affect their ability to fully take part in the trial
• People currently participating in another clinical trial that could conflict with this study
• People who are currently receiving upper limb rehabilitation from a licensed therapist within 4 weeks of the screening visit and through to the primary study endpoint
• Employees of the company sponsoring the trial
• People who are currently in prison

Important: Always verify eligibility with the trial site directly before applying.