Alzheimer's Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 55 years or older who are already part of an existing long-term research study called the Baltimore Longitudinal Study of Aging (BLSA)
• People who have already had an MRI scan as part of the BLSA study, or who have agreed to have one
• People who are able to understand and agree to participate in the study on their own (the ability to give consent is assessed as part of the regular BLSA visit)

Who may not be able to join:

• People younger than 55 years of age
• People who are pregnant
• People who have a pre-existing disease of the brain or central nervous system (the brain and spinal cord)
• People who weigh more than 300 lbs
• People with active cancer that has spread to other parts of the body (skin cancer of the basal cell type is an exception)
• People with a pacemaker or any implanted electronic hearing device
• People who have had breast cancer treated with radiation
• People who have lymphoma (a type of blood cancer)
• People who have a brain tumour
• People who have metal shrapnel in their body
• People with schizophrenia
• People with bipolar disorder
• People with epilepsy
• People who have a language barrier that makes communication during the study difficult
• People with a brain aneurysm larger than 3mm, or who have aneurysm clips (small metal devices used to treat aneurysms)
• People with Parkinson's disease, or who take medications used to treat Parkinson's disease
• People with Huntington's disease
• People with poorly controlled diabetes (specifically, a blood sugar measurement called HbA1c above 8); treated and well-controlled diabetes is generally acceptable (confirm with trial site)
• People with severe hormonal or gland-related conditions; treated thyroid conditions are generally acceptable (confirm with trial site)
• People who have been diagnosed with dementia or mild cognitive impairment
• People who are not eligible to have an MRI scan for any reason
• People who have had a stroke, or who have had a series of small strokes (called TIAs) that required a hospital stay
• People with known abnormal blood vessels or certain types of growths in the brain
• People with a history of significant exposure to radiation
• People who score 4 or higher on a memory and thinking assessment used within the BLSA will need to be reviewed by a research panel to rule out dementia before a decision on participation is made

Important: Always verify eligibility with the trial site directly before applying.