Phase 1 Motor Neurone Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with ALS (also known as Lou Gehrig's disease) — as definite, possible, or probable — by a doctor who specializes in managing this condition.
• Your ALS symptoms started no more than 24 months (2 years) before your screening appointment, as determined by the study doctor.
• Your Body Mass Index (BMI) — a measure of body weight relative to height — is between 18.0 and 35.0.

Who may not be able to join:

• You have a history of, or currently have, a significant medical condition affecting the heart, kidneys, liver, stomach or gut, lungs, blood, hormones, mental health, or nervous system, or you have had seizures, or have abnormal results on certain medical tests.
• You have been diagnosed with another disease that affects the brain or nervous system over time, or you have significant memory loss or severe thinking/cognitive problems.
• Your blood test results show that certain liver-related values (ALT, AST, or total bilirubin) are more than twice the normal upper limit.
• Your kidneys are not functioning well enough, based on a specific measure of kidney filtering ability falling below a certain level (confirm with trial site).
• Your heart's electrical activity, measured by a specific heart tracing test (ECG) done at screening, shows abnormalities that the study doctor believes could make participation risky.
• You have significant abnormalities in your lower spine, either known beforehand or found during screening X-rays or imaging scans (if these are performed).

Important: Always verify eligibility with the trial site directly before applying.