Ovarian Cancer Trial, Recruiting NCT07102797 Sponsor: Massachusetts General Hospital Condition: Ovarian Cancer
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Ovarian Cancer Trial, Recruiting

NCT07102797
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For the caregiver (parent or guardian):

  • The child's mother, father, or other legal guardian
  • Someone who speaks English
  • Someone who has access to a phone or computer that can receive emails or text messages from the study team

For the child:

  • A girl between 8 and 12 years old at the time of joining the study
  • Someone who speaks English
  • A girl who has not yet started her period
  • A girl considered at risk for Polycystic Ovary Syndrome (PCOS) or insulin resistance, meaning at least one of the following applies: her mother had PCOS or gestational diabetes (diabetes during pregnancy); her body weight is at or above the 85th percentile for her age; she has had early onset of puberty-related hormone changes (called premature adrenarche); or she was born smaller than expected for how far along the pregnancy was

Who may not be able to join:

  • Girls currently taking certain medications, including metformin, GLP-1 receptor agonist medications (a type of diabetes or weight medication), insulin, or hormone-suppressing medications (GnRH agonists)
  • Girls with certain hormonal or gland conditions that affect insulin sensitivity, male hormone levels, or growth
  • Girls diagnosed with Type 1 diabetes, Type 2 diabetes, or a condition called Congenital Hyperinsulinism (a condition causing abnormally high insulin levels from birth)
  • Girls with a tumour on the adrenal gland or a condition called Congenital Adrenal Hyperplasia (a hormone disorder present from birth)
  • Girls with an overactive thyroid, or an underactive thyroid that is not well controlled
  • Girls with Growth Hormone Deficiency
  • Girls with heart, nerve, or muscle/joint conditions that would prevent them from taking part in physical activity, including Type 1 diabetes in this context
  • Girls with serious additional health conditions including severe heart defects from birth, major physical birth differences, cystic fibrosis, cerebral palsy, conditions requiring tube feeding, undiagnosed conditions significantly affecting growth and development, or serious heart, liver, cancer, inflammatory, or psychiatric conditions

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 6176434585

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
24 November 2025
Est. completion
1 December 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Retention; Acceptability

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov