Phase 3 Alzheimer's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 50 years or older, of any gender
- People who are able to undergo both PET scans and MRI scans
- People who are willing to use contraception during the study and for 6 months after it ends
- People who have provided written consent before any study assessments begin
For people with no memory or thinking problems, the following additional criteria apply:
- A score of 0 on a standard memory and thinking assessment called the CDR
- A score of 28 or higher on another standard thinking test called the MMSE
- A brain scan showing no signs of a certain protein buildup (called amyloid) associated with Alzheimer's disease
For people with mild cognitive impairment (early memory or thinking difficulties):
- A diagnosis of mild cognitive impairment that meets specific international medical guidelines from 2011
- A brain scan showing signs of the amyloid protein buildup
For people with Alzheimer's disease:
- A diagnosis that meets specific international medical guidelines from 2014
- A brain scan showing signs of the amyloid protein buildup
Who may not be able to join:
- People diagnosed with certain other types of dementia or related brain conditions, such as Lewy body dementia or frontotemporal dementia
- People currently experiencing significant mental health symptoms that would prevent them from completing the scans
- People whose MRI has shown significant structural brain abnormalities, such as a large stroke or a growth in the brain
- People who experience severe anxiety in enclosed spaces (claustrophobia)
- People with a history of alcohol or drug misuse or dependence
- People who have a known allergy to the study drug or any of its ingredients
- People who are currently breastfeeding
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Jiong Shi, Doctor, The First Affiliated Hospital of University of Science and Technology of China
Phone: 15512191857
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Evaluate the effectiveness of visual reading of XTR006 PET imaging in detecting tau NFTs (neurofibrillary tangles)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.