Phase 2 Oesophageal Cancer Trial, Recruiting NCT07132918 Sponsor: University of Wisconsin, Madison Condition: Oesophageal Cancer
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Phase 2 Oesophageal Cancer Trial, Recruiting

NCT07132918
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must be 18 years of age or older at the time of signing the consent form.
  • Based on a quick automated planning scan, a certain amount of radiation would reach your heart (specifically, more than 10% of your heart would receive more than 25 Gray units of radiation) — (confirm with trial site if unsure what this means for you).
  • You have been diagnosed with one of the following cancers, confirmed by a tissue or cell sample: certain stages of non-small cell lung cancer that cannot be treated with surgery (Stage IIB, IIIA, IIIB, IIIC, or IV); limited stage small cell lung cancer treated once daily; Stage I–III esophageal or esophagogastric (food pipe/stomach junction) cancer; Stage II or III thymoma or thymic carcinoma (cancers of the thymus gland); or other cancers in the chest area that meet the trial's specific requirements, such as lymphoma or sarcoma.
  • Your planned radiation treatment must involve at least 15 daily sessions, with each session typically delivering between 1.8 and 4 Gray units of radiation.

Who may not be able to join:

  • You have clear signs that your cancer has spread to other parts of the body and your life expectancy is less than 12 months.
  • You have previously had radiation therapy to the chest area that significantly overlapped with your heart.
  • You have a medical reason why you cannot have an MRI scan.
  • You have serious, active heart problems classified as Level III or IV under the New York Heart Association scale, meaning significant limitations in physical activity due to heart symptoms (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Carri Glide-Hurst, PhD, DABR, FAAPM, University of Wisconsin, Madison

Phone: 800-622-8922

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
8 October 2025
Est. completion
1 March 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in left ventricular ejection fraction (LVEF)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov