Stroke Trial, Recruiting NCT07134777 Sponsor: University of Rochester Condition: Stroke
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Stroke Trial, Recruiting

NCT07134777
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People between 21 and 80 years of age
  • People who currently live in the United States or Canada
  • People who have had a stroke or stroke-like injury to a specific part of the brain responsible for vision (the primary visual cortex or nearby nerve fibres), which occurred between the ages of 21 and 80, confirmed by MRI or CT scan
  • People who have a consistent blind or partially blind area affecting the same region in both eyes (called a homonymous visual field defect), large enough to cover a specific area of vision, as measured by standard vision field tests
  • People who are able to hold their gaze steadily on a target for at least one second without their eyes wandering more than a very small amount (this will be checked more thoroughly once testing begins in the lab)
  • People who are willing and able to give their own informed consent to take part
  • People who have access to their own desktop or laptop computer and a reliable internet connection at home
  • People who have normal thinking and memory abilities, and who can understand and follow spoken and written instructions in English well enough to complete several months of visual training at home independently
  • People who are able to speak and understand English (the trial is unable to support participants who require interpreter services)
  • People who are willing and medically safe to undergo MRI scans

Who may not be able to join:

  • People who have a past or current eye disease that affects their vision clarity
  • People whose best corrected vision (with glasses or contact lenses) is worse than 20/40 in either eye
  • People who have confirmed or suspected damage to a specific brain relay station involved in vision (the dorsal Lateral Geniculate Nucleus)
  • People who have a condition causing widespread deterioration across the whole brain
  • People who have had a traumatic brain injury
  • People who have any other brain damage that trial staff consider likely to affect training ability or results
  • People who have eye movement problems that trial staff consider likely to interfere with the ability to hold a steady gaze during testing or training
  • People with a documented history of drug or alcohol misuse
  • People currently taking medications that affect the brain or nervous system in ways that could impact training, as determined by the lead researcher
  • People who have cognitive difficulties, memory disorders, or seizure disorders
  • People who experience one-sided attentional neglect (a condition where a person is unaware of things on one side of their environment)
  • People who are unable to carry out the visual training exercises as instructed
  • People who have any of the following, which are incompatible with MRI scanning: brain aneurysm clips, implanted nerve stimulators, implanted heart pacemakers or defibrillators, cochlear implants, metal fragments in the eye, insulin pumps, metal shrapnel or bullets, or any other implanted device that cannot safely be used with an MRI machine
  • People who have conditions that prevent MRI scanning, such as severe obesity or claustrophobia

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 9 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 585-275-5234

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
17 October 2025
Est. completion
1 August 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Identify visual areas of damage; Characterize visual response prior to visual training; Characterize how visual response properties in residual visual areas change following a period of visual training

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 9 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov