COPD Trial, Recruiting NCT07135583 Sponsor: Thomas Jefferson University Condition: COPD
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COPD Trial, Recruiting

NCT07135583
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults between 18 and 70 years of age
  • People who have had a spinal cord injury (SCI) for at least 1 year, with the injury located at or below a specific level of the spine (between the third cervical and eighth thoracic vertebrae)
  • People with an incomplete spinal cord injury, meaning some signals can still pass through the injured area (classified as incomplete-B, C, or D)
  • People who are medically stable and have received clearance from their doctor to participate
  • People whose spinal cord injury was caused by a non-progressive condition, meaning the underlying cause is not continuing to worsen
  • People who have more than 20% reduction in their ability to breathe in or breathe out with full effort, compared to normal levels

Who may not be able to join:

  • People who have been diagnosed with another neurological condition, such as multiple sclerosis or stroke
  • People who show no diaphragm muscle activity during forced breathing tests
  • People who are currently experiencing a serious illness or infection
  • People with wounds (pressure ulcers) that are not healing
  • People with an untreated bladder or urinary tract infection
  • People with cardiovascular (heart or blood vessel) disease
  • People with a lung disease
  • People with active heterotopic ossification, a condition where bone tissue forms in abnormal places in the body (confirm with trial site)
  • People with uncontrolled high blood pressure
  • People experiencing severe nerve pain
  • People who are pregnant
  • People who experience severe, recurring, and uncontrolled autonomic dysreflexia, a condition where the nervous system overreacts causing sudden changes in blood pressure and other symptoms (confirm with trial site)
  • People with a history of seizure disorder

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Jay Nair, PT, PhD, Thomas Jefferson University

Phone: 13528715888

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Thomas Jefferson University
Registry
ClinicalTrials.gov
Start date
18 September 2025
Est. completion
15 August 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

change in mouth occlusion pressure at 0.1 secs (P0.1)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov